Monday, August 18, 2008

Circadian Rhythm-Metabolism Link Discovered

Researchers at the University of California, Irvine have discovered a protein that senses energy usage in our cells. This protein, called SRT1, works in concert with a circadian rhythm protein called CLOCK to regulate our cells’ activities. When the balance between these proteins is disrupted, say by poor sleep or diet patterns, normal cell functions can become upset in the process. This discovery of a link between a protein involved in cell metabolism and one involved in circadian rhythms demonstrates how sleep disturbance can lead to metabolic problems such as obesity, diabetes, and even accelerated aging.

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